Pesquisa sobre:
UNFOLDED PROTEIN RESPONSE
Descritores Encontrados:
1
Mostrando:
1 .. 1
1 / 1
DeCS
Descritor
Inglês
:
Unfolded Protein Response
Descritor
Espanhol
:
Respuesta de Proteína Desplegada
Descritor
Português
:
Resposta a Proteínas não Dobradas
Categoria:
G02.111.087.675.871.790.600.962
G02.111.087.693.600.850
G02.149.115.675.871.790.600.850
G02.149.115.693.600.925
G03.495.770.871.790.600.850
G05.355.315.670.600.850
Definição
Inglês
:
A cellular response to environmental insults that cause disruptions in
PROTEIN FOLDING
and/or accumulation of defectively folded protein in the
ENDOPLASMIC RETICULUM
. It consists of a group of regulatory cascades that are triggered as a response to altered levels of
calcium
and/or the redox
state
of the
endoplasmic reticulum
. Persistent activation of the
unfolded protein response
leads to the induction of
APOPTOSIS.
Nota Histórica
Inglês
:
2010
Qualificadores Permitidos
Inglês
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Número do Registro:
53752
Identificador Único:
D056811
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS